8/7/09   Genetic profiling of tumors could have 'immediate impact' on treating cancer. New work by KI cancer biologists shows that the interplay between two key genes that are often defective in tumors accurately predicts response to chemotherapy. 

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7/30/09 Tiny particles carrying a toxin gene can effectively suppress ovarian tumor growth in mice, according to a team of researchers from KI and the Lankenau Institute. The findings could lead to a new treatment for ovarian cancer, which now causes more than 15,000 deaths each year in the United States. Because it is usually diagnosed at a relatively late stage, ovarian cancer is one of the most deadly forms of the disease.

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7/21/09 Intrigued by the idea of artificial organs, a biomedical engineer uses computer-chip technology to craft tiny livers that may transform the way liver tissues can be repaired and how new drugs are screened.  Whether inventing "micro-livers", developing next-gen cancer drugs, mentoring students in her KI Lab, or showing kids that math and science are fun, KI's Sangeeta Bhatia is a "down to earth" engineer role model.

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7/9/09 mTOR is in the spotlight again.  Forbes reports on mTOR's role at the junction of aging and cancer.  Exactly how this protein does this isn't clear. One possibility is that mTOR is turned on by starvation--a well characterized life extending pathway.  What's enticing about these new findings is what they may say about the biology of aging and how this research intersects with one of the hotter areas in cancer drug research.

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6/26/09  A pH responsive film that releases drugs to kill cancer cells could find applications from implant coatings to drug delivery systems, say scientists in the US and Korea. As part of the team, KI's Paula Hammond says there is important commercial potential for localized delivery of cancer therapeutics and vaccines.  

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